Full time equivalents (FTEs) are committed full time to the sponsor. FTE-based projects are quoted on time and materials, with back-charge of raw materials. These are research oriented projects and/or difficult projects, where the substantial technical risks preclude quoting a fixed price. FTE projects generally involve smaller amounts of material (500 mg to 50 grams). Additional benefits for contracting full time equivalents (FTE) versus contracting multiple one-off type projects include:

• Reliable Capacity: FTE contracts provide our clients consistent and reliable laboratory capacity. In a one-off situation, timely project start-up maybe hampered by inadequate available personnel.
• Flexibility and Responsiveness: The data-driven dynamics of the drug discovery environment often necessitates changes in goals. For example, late-breaking biological or physicochemical data on an investigational molecule will prompt its deprioritization in favor of another lead. Consequently, the scale-up synthesis of a target molecule may need to be modified mid-stream or suspended. The FTE approach allows for projects to change without the need to adjust a work order.
• Project Execution Facilitation: Projects may be initiated immediately when the chemistry is provided, there is no time lapse for proposal writing and contract approval process.

Relationships are absolutely essential to the success of all outsourcing initiatives. We typically undertake one-off projects initially where Adesis, Inc. assumes the risk during the crucial getting acquainted period. Shared risk can then be considered, if mutually agreeable, such as:

• One-off projects and catalog sales initially (cf, vide infra)
• Evolve to FTEs for appropriate projects
• Blend of one-off, FTE and catalog sales offers best value to both parties.

In addition to expeditious synthesis campaigns, we also maximize value for customers through our operations. For example, FTE projects have the support of a full service kilo lab on the same site to make unavailable raw materials as one-offs. This allows the sponsor considerable budget flexibility and ensures that projects will not be delayed because of raw material backorders.